The ARM mbed USB MSD bootloader which is used on many silicon vendor boards has a big problem: it is vulnerable to operating systems like Windows 10 which can brick your board (see “Bricking and Recovering OpenSDA Boards in Windows 8 and 10“). To recover the board, typically a JTAG/SWD programmer has to be used. I have described in articles (see links section) how to recover from that situation, including using an inofficial new bootloader which (mostly) solves the problem. The good news is that ARM (mbed) has released an official and fixed bootloader. The bad news is that this bootloader does not work on every board because of a timing issue: the bootloader mostly enters bootloader mode instated executing the application.